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Cancer cells interact with each other and with the microenvironment, fostering tumor diversity and evolution. This Review discusses the etiology and clinical implications of intra-tumor heterogeneity and outlines novel theutic approaches that account for tumor diversity and evolution.
Clinical investigations using stem cell products are addressing a wide spectrum of conditions using many different stem cell types. Trounson and McDonald review the clinical trials in which data have now been published and highlight areas where progress is being made as well as failures and areas of concern.
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Latest results, headlines and video, candidates’ positions on the issues, fundraising totals, States to Watch news and analysis, and a unique side-by-side visual comparison of the Republican and Democratic presidential candidates.
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